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Structure of the Human Telomere in K(+) Solution: An Intramolecular (3 + 1) G-Quadruplex Scaffold

We present the intramolecular G-quadruplex structure of human telomeric DNA in physiologically relevant K(+) solution. This G-quadruplex, whose (3 + 1) topology differs from folds reported previously in Na(+) solution and in a K(+)-containing crystal, involves the following: one anti•syn•syn•syn and...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Luu, Kim Ngoc, Phan, Anh Tuân, Kuryavyi, Vitaly, Lacroix, Laurent, Patel, Dinshaw J.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692383/
https://ncbi.nlm.nih.gov/pubmed/16866556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062791w
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