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DNA Adduct Structure–Function Relationships: Comparing Solution with Polymerase Structures

It has now been nearly two decades since the first solution structures of DNA duplexes covalently damaged by metabolically activated polycyclic aromatic hydrocarbons and amines were determined by NMR. Dozens of such high-resolution structures are now available, and some broad structural themes have...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Res Toxicol
Hauptverfasser: Broyde, Suse, Wang, Lihua, Zhang, Ling, Rechkoblit, Olga, Geacintov, Nicholas E., Patel, Dinshaw J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692375/
https://ncbi.nlm.nih.gov/pubmed/18052109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700193x
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