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Diseases caused by mutations in ORAI1 and STIM1

Ca(2+) release-activated Ca(2+) (CRAC) channels mediate a specific form of Ca(2+) influx called store-operated Ca(2+) entry (SOCE) that contributes to the function of many cell types. CRAC channels are formed by ORAI1 proteins located in the plasma membrane, which form its ion-conducting pore. ORAI1...

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Bibliografiska uppgifter
I publikationen:Ann N Y Acad Sci
Huvudupphovsmän: Lacruz, Rodrigo S., Feske, Stefan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692058/
https://ncbi.nlm.nih.gov/pubmed/26469693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12938
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