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Diseases caused by mutations in ORAI1 and STIM1
Ca(2+) release-activated Ca(2+) (CRAC) channels mediate a specific form of Ca(2+) influx called store-operated Ca(2+) entry (SOCE) that contributes to the function of many cell types. CRAC channels are formed by ORAI1 proteins located in the plasma membrane, which form its ion-conducting pore. ORAI1...
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| Udgivet i: | Ann N Y Acad Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692058/ https://ncbi.nlm.nih.gov/pubmed/26469693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12938 |
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