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Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity
Store-operated Ca(2+) entry (SOCE) in cells of the immune system is mediated by Ca(2+) release-activated Ca(2+) (CRAC) channels that are formed by ORAI1 and its homologues ORAI2 and ORAI3. They are activated by stromal interaction molecules (STIM) 1 and 2 in response to depletion of endoplasmic reti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3473275/ https://ncbi.nlm.nih.gov/pubmed/22615435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.233221 |
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