Fenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic β-cells

AIM: To investigate the effect of fenugreek lactone (FL) on palmitate (PA)-induced apoptosis and dysfunction in insulin secretion in pancreatic NIT-1 β-cells. METHODS: Cells were cultured in the presence or absence of FL and PA (0.25 mmol/L) for 48 h. Then, lipid droplets in NIT-1 cells were observe...

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Podrobná bibliografie
Vydáno v:World J Gastroenterol
Hlavní autoři: Gong, Jing, Dong, Hui, Jiang, Shu-Jun, Wang, Ding-Kun, Fang, Ke, Yang, De-Sen, Zou, Xin, Xu, Li-Jun, Wang, Kai-Fu, Lu, Fu-Er
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2015
Témata:
Basic Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690174/
https://ncbi.nlm.nih.gov/pubmed/26730156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i48.13457
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