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Metformin induces apoptosis of pancreatic cancer cells

AIM: To assess the role and mechanism of metformin in inducing apoptosis of pancreatic cancer cells. METHODS: The human pancreatic cancer cell lines ASPC-1, BxPc-3, PANC-1 and SW1990 were exposed to metformin. The inhibition of cell proliferation and colony formation via apoptosis induction and S ph...

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Publicado en:World J Gastroenterol
Main Authors: Wang, Luo-Wei, Li, Zhao-Shen, Zou, Duo-Wu, Jin, Zhen-Dong, Gao, Jun, Xu, Guo-Ming
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988356/
https://ncbi.nlm.nih.gov/pubmed/19084933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v14.i47.7192
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