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SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction
Abnormally high levels of circulating free fatty acids can lead to pancreatic islet β-cell dysfunction and apoptosis, contributing to β-cell failure in Type 2 diabetes. The NAD(+)-dependent protein deacetylase Sirtuin-3 (SIRT3) has been implicated in Type 2 diabetes. In this study, we tested whether...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4411148/ https://ncbi.nlm.nih.gov/pubmed/25915406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124744 |
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