Retinoid X Receptor α Overexpression Alleviates Mitochondrial Dysfunction-induced Insulin Resistance through Transcriptional Regulation of Insulin Receptor Substrate 1

Mitochondrial dysfunction is associated with insulin resistance and diabetes. We previously showed that retinoid X receptor α (RXRα) played an important role in transcriptional regulation of oxidative phosphorylation (OXPHOS) genes in cells with mitochondrial dysfunction caused by mitochondrial DNA...

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Publicat a:Mol Cells
Autors principals: Lee, Seung Eun, Koo, Young Do, Lee, Ji Seon, Kwak, Soo Heon, Jung, Hye Seung, Cho, Young Min, Park, Young Joo, Chung, Sung Soo, Park, Kyong Soo
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400311/
https://ncbi.nlm.nih.gov/pubmed/25728751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.2280
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