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GRK2 Compromises Cardiomyocyte Mitochondrial Function by Diminishing Fatty Acid-Mediated Oxygen Consumption and Increasing Superoxide Levels
The G protein-coupled receptor kinase-2 (GRK2) is upregulated in the injured heart and contributes to heart failure pathogenesis. GRK2 was recently shown to associate with mitochondria but its functional impact in myocytes due to this localization is unclear. This study was undertaken to determine t...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689631/ https://ncbi.nlm.nih.gov/pubmed/26506135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.10.002 |
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