Phosphoinositide Dependent Protein Kinase 1 is Required for Exercise-induced Cardiac Hypertrophy but not the Associated Mitochondrial Adaptations

Phosphoinositide-dependent protein kinase-1 (PDPK1) is an important mediator of phosphatidylinositol 3-kinase (PI3K) signaling. We previously reported that PI3K but not Akt signaling mediates the increase of mitochondrial oxidative capacity to physiological cardiac hypertrophy. To determine if PDPK1...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Noh, Junghyun, Wende, Adam R., Olsen, Curtis D, Kim, Bumjun, Bevins, Jack, Zhu, Yi, Zhang, Quan-Jiang, Riehle, Christian, Abel, E. Dale
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689617/
https://ncbi.nlm.nih.gov/pubmed/26476238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.10.015
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