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Decitabine Nano-conjugate Sensitizing Human Glioblastoma Cells to Temozolomide
In this study we developed and characterized a delivery system for the epigenetic demethylating drug, decitabine, to sensitize temozolomide-resistant human glioblastoma multiforme (GBM) cells to alkylating chemotherapy. A poly(lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) based nano-...
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| Izdano u: | Mol Pharm |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689316/ https://ncbi.nlm.nih.gov/pubmed/25751281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500815b |
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