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A DNA delivery system containing listeriolysin O results in enhanced hepatocyte-directed gene expression
AIM: To determine whether incorporation of the pH-dependent ba cterial toxin listeriolysin O (LLO) into the DNA carrier system could increase the endosomal escape of internalized DNA and result gene expression. METHODS: A multi-component delivery system was prepared consist ing of asialoglycoprotein...
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| Publicat a: | World J Gastroenterol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Baishideng Publishing Group Inc
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688787/ https://ncbi.nlm.nih.gov/pubmed/11819493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v5.i6.465 |
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