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Targeted transplantation of mitochondria to hepatocytes

BACKGROUND: Mitochondrial defects in hepatocytes can result in liver dysfunction and death. Hepatocytes have cell-surface asialoglycoprotein receptors (AsGRs) which internalize AsGs within endosomes. The aim of this study was to determine whether mitochondria could be targeted to hepatocytes by AsGR...

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Detalhes bibliográficos
Publicado no:Hepat Med
Main Authors: Gupta, Nidhi, Wu, Catherine H, Wu, George Y
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136362/
https://ncbi.nlm.nih.gov/pubmed/27942238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HMER.S116852
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