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A DNA delivery system containing listeriolysin O results in enhanced hepatocyte-directed gene expression
AIM: To determine whether incorporation of the pH-dependent ba cterial toxin listeriolysin O (LLO) into the DNA carrier system could increase the endosomal escape of internalized DNA and result gene expression. METHODS: A multi-component delivery system was prepared consist ing of asialoglycoprotein...
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| Publicado no: | World J Gastroenterol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688787/ https://ncbi.nlm.nih.gov/pubmed/11819493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v5.i6.465 |
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