Bacterial delivery of large intact genomic-DNA-containing BACs into mammalian cells

Efficient delivery of large intact vectors into mammalian cells remains problematical. Here we evaluate delivery by bacterial invasion of two large BACs of more than 150 kb in size into various cells. First, we determined the effect of several drugs on bacterial delivery of a small plasmid into diff...

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Detalhes bibliográficos
Main Authors: Cheung, Wing, Kotzamanis, George, Abdulrazzak, Hassan, Goussard, Sylvie, Kaname, Tadashi, Kotsinas, Athanassios, Gorgoulis, Vassilis G., Grillot-Courvalin, Catherine, Huxley, Clare
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357338/
https://ncbi.nlm.nih.gov/pubmed/22095052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.18621
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