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Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats
OBJECTIVE: To introduce a genetic survival advantage for transplanted human hepatocytes over host cells in rats. METHODS: Green fluorescent protein (GFP) was introduced into Huh7 human hepatoma cells to create fluorescent GFP-Huh7 cells. mRNA of CYP2E1, the enzyme that converts acetaminophen (APA) i...
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| Publicado no: | J Dig Dis |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4676072/ https://ncbi.nlm.nih.gov/pubmed/23107445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-2980.2012.00632.x |
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