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Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats

OBJECTIVE: To introduce a genetic survival advantage for transplanted human hepatocytes over host cells in rats. METHODS: Green fluorescent protein (GFP) was introduced into Huh7 human hepatoma cells to create fluorescent GFP-Huh7 cells. mRNA of CYP2E1, the enzyme that converts acetaminophen (APA) i...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Dig Dis
Päätekijät: SMOLIC, Martina, WU, Catherine H., MADADI, Shilpa, GUPTA, Nidhi, SMOLIC, Robert, COASH, Marcy, SMIT, Jeanette, WU, George Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676072/
https://ncbi.nlm.nih.gov/pubmed/23107445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-2980.2012.00632.x
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