Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU): resulting drug levels and modulation of oxylipin pattern

Epoxides from polyunsaturated fatty acids (PUFAs) are potent lipid mediators. In vivo stabilization of these epoxides by blockade of the soluble epoxide hydrolase (sEH) leads to anti-inflammatory, analgesic and normotensive effects. Therefore, sEH inhibitors (sEHi) are a promising new class of drugs...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Prostaglandins Other Lipid Mediat
Asıl Yazarlar: Ostermann, Annika I., Herbers, Jan, Willenberg, Ina, Chen, Rongjun, Hwang, Sung Hee, Greite, Robert, Morisseau, Christophe, Gueler, Faikah, Hammock, Bruce D., Schebb, Nils Helge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688279/
https://ncbi.nlm.nih.gov/pubmed/26117215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2015.06.005
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller