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A Soluble Epoxide Hydrolase Inhibitor, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis

Polyunsaturated fatty acids (PUFAs) are essential FAs for human health. Cytochrome P450 oxygenates PUFAs to produce anti-inflammatory and pain-resolving epoxy fatty acids (EpFAs) and other oxylipins whose epoxide ring is opened by the soluble epoxide hydrolase (sEH/Ephx2), resulting in the formation...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Jonnalagadda, Deepa, Wan, Debin, Chun, Jerold, Hammock, Bruce D., Kihara, Yasuyuki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125305/
https://ncbi.nlm.nih.gov/pubmed/33925035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094650
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