Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) has attracted great interest as a cancer therapy because it selectively induces death receptor (DR)-mediated apoptosis in cancer cells while sparing normal tissue. However, recombinant human TRAIL demonstrates limited therapeutic effica...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Oh, Yumin, Swierczewska, Magdalena, Kim, Tae Hyung, Lim, Sung Mook, Eom, Ha Na, Park, Jae Hyung, Na, Dong Hee, Kim, Kwangmeyung, Lee, Kang Choon, Pomper, Martin G., Lee, Seulki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688186/
https://ncbi.nlm.nih.gov/pubmed/26381901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.014
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