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Smad7 Protein Induces Interferon Regulatory Factor 1-dependent Transcriptional Activation of Caspase 8 to Restore Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis

Smad7 has been known as a negative regulator for the transforming growth factor-β (TGF-β) signaling pathway through feedback regulation. However, Smad7 has been suspected to have other biological roles through the regulation of gene transcription. By screening differentially regulated genes, we foun...

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Detalhes bibliográficos
Main Authors: Hong, Suntaek, Kim, Hye-Youn, Kim, Jooyoung, Ha, Huyen Trang, Kim, Young-Mi, Bae, Eunjin, Kim, Tae Hyung, Lee, Kang Choon, Kim, Seong-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561575/
https://ncbi.nlm.nih.gov/pubmed/23255602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400408
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