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What is the future of PEGylated therapies?
The tremendous potential of biologic drugs is hampered by short half-lives in vivo, resulting in significantly lower potency than activity seen in vitro. These short-acting therapeutic agents require frequent dosing profiles that can reduce applicability to the clinic, particularly for chronic condi...
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| Publicado no: | Expert Opin Emerg Drugs |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4908577/ https://ncbi.nlm.nih.gov/pubmed/26583759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728214.2015.1113254 |
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