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Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells
Tumor cells disseminate into compartments that are poorly accessible from circulation, which necessitates high doses of systemic chemotherapy. However, the effectiveness of many drugs, such as the potent topoisomerase I poison SN-38, are hampered by poor pharmacokinetics. To deliver SN-38 to lymphom...
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| Publicado no: | Sci Transl Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687972/ https://ncbi.nlm.nih.gov/pubmed/26062846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa5447 |
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