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Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy
The MAPK signal transduction cascade is dysregulated in a majority of human tumors. Here we report that a nanoparticle-mediated targeting of this pathway can optimize cancer chemotherapy. We engineered nanoparticles from a unique hexadentate-polyD,L-lactic acid-co-glycolic acid polymer chemically co...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683142/ https://ncbi.nlm.nih.gov/pubmed/19383798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902857106 |
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