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Rationally engineered polymeric cisplatin nanoparticle for improved antitumor efficacy
The use of cisplatin, a first line chemotherapy for most cancers, is dose-limited due to nephrotoxicity. While, this toxicity can be addressed through nanotechnology, previous attempts at engineering cisplatin nanoparticles have been limited by the impact on the potency of cisplatin. Here we report...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158969/ https://ncbi.nlm.nih.gov/pubmed/21576779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0957-4484/22/26/265101 |
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