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Mechanistic studies of Gemcitabine-loaded nanoplatforms in resistant pancreatic cancer cells

BACKGROUND: Pancreatic cancer remains the deadliest of all cancers, with a mortality rate of 91%. Gemcitabine is considered the gold chemotherapeutic standard, but only marginally improves life-span due to its chemical instability and low cell penetrance. A new paradigm to improve Gemcitabine’s ther...

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Detalhes bibliográficos
Main Authors: Papa, Anne-Laure, Basu, Sudipta, Sengupta, Poulomi, Banerjee, Deboshri, Sengupta, Shiladitya, Harfouche, Rania
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543259/
https://ncbi.nlm.nih.gov/pubmed/22998550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-419
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