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Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation

Serotonin is a ubiquitous chemical transmitter with particularly important roles in the gastrointestinal, cardiovascular and central nervous systems. Modulation of serotonergic signaling occurs, in part, by uptake of the transmitter by the serotonin transporter (SERT). In the brain, SERT is the targ...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Green, Evan M., Coleman, Jonathan A., Gouaux, Eric
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687910/
https://ncbi.nlm.nih.gov/pubmed/26695939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145688
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