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Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation

Serotonin is a ubiquitous chemical transmitter with particularly important roles in the gastrointestinal, cardiovascular and central nervous systems. Modulation of serotonergic signaling occurs, in part, by uptake of the transmitter by the serotonin transporter (SERT). In the brain, SERT is the targ...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Green, Evan M., Coleman, Jonathan A., Gouaux, Eric
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687910/
https://ncbi.nlm.nih.gov/pubmed/26695939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145688
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