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X-ray structures and mechanism of the human serotonin transporter
The serotonin transporter (SERT) terminates serotonergic signaling through the sodium and chloride dependent reuptake of neurotransmitter into presynaptic neurons. SERT is a target for antidepressant and psychostimulant drugs, which block reuptake and prolong neurotransmitter signaling. Here we repo...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4898786/ https://ncbi.nlm.nih.gov/pubmed/27049939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17629 |
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