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X-ray structures and mechanism of the human serotonin transporter
The serotonin transporter (SERT) terminates serotonergic signaling through the sodium and chloride dependent reuptake of neurotransmitter into presynaptic neurons. SERT is a target for antidepressant and psychostimulant drugs, which block reuptake and prolong neurotransmitter signaling. Here we repo...
Salvato in:
| Pubblicato in: | Nature |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4898786/ https://ncbi.nlm.nih.gov/pubmed/27049939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17629 |
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