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Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel
Flux-dependent inactivation that arises from functional coupling between the inner gate and the selectivity filter is widespread in ion channels. The structural basis of this coupling has only been well characterized in KcsA. Here we present NMR data demonstrating structural and dynamic coupling bet...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687598/ https://ncbi.nlm.nih.gov/pubmed/26621745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515965112 |
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