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A single NaK channel conformation is not enough for non-selective ion conduction

NaK and other non-selective channels are able to conduct both sodium (Na(+)) and potassium (K(+)) with equally high efficiency. In contrast to previous crystallographic results, we show that the selectivity filter (SF) of NaK in native-like lipid membranes adopts two distinct conformations that are...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Shi, Chaowei, He, Yao, Hendriks, Kitty, de Groot, Bert L., Cai, Xiaoying, Tian, Changlin, Lange, Adam, Sun, Han
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818664/
https://ncbi.nlm.nih.gov/pubmed/29459730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03179-y
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