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Conduction of Na(+) and K(+) through the NaK Channel: Molecular and Brownian Dynamics Studies
Conduction of ions through the NaK channel, with M0 helix removed, was studied using both Brownian dynamics and molecular dynamics. Brownian dynamics simulations predict that the truncated NaK has approximately a third of the conductance of the related KcsA K(+) channel, is outwardly rectifying, and...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483743/ https://ncbi.nlm.nih.gov/pubmed/18456826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.126722 |
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