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Conduction of Na(+) and K(+) through the NaK Channel: Molecular and Brownian Dynamics Studies

Conduction of ions through the NaK channel, with M0 helix removed, was studied using both Brownian dynamics and molecular dynamics. Brownian dynamics simulations predict that the truncated NaK has approximately a third of the conductance of the related KcsA K(+) channel, is outwardly rectifying, and...

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Bibliografiske detaljer
Main Authors: Vora, Taira, Bisset, David, Chung, Shin-Ho
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483743/
https://ncbi.nlm.nih.gov/pubmed/18456826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.126722
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