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Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism
Type 2 diabetes is characterized by a reduction in insulin function and an increase in glucagon activity that together result in hyperglycemia. Glucagon receptor antagonists have been developed as drugs for diabetes; however, they often increase glucagon plasma levels and induce the proliferation of...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687559/ https://ncbi.nlm.nih.gov/pubmed/26621734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513872112 |
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