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Next Generation Sequencing to Characterize Mitochondrial Genomic DNA Heteroplasmy

This protocol is to describe the methodology to characterize mitochondria DNA (mtDNA) heteroplasmy with parallel sequencing. Mitochondria play a very important role in important cellular functions. Each eukaryotic cell contains hundreds of mitochondria with hundreds of mitochondria genomes. The muta...

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Bibliographic Details
Published in:Curr Protoc Hum Genet
Main Author: Huang, Taosheng
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687495/
https://ncbi.nlm.nih.gov/pubmed/21975941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142905.hg1908s71
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