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Assessing mitochondrial heteroplasmy using next generation sequencing: A note of caution

The mitochondrial genome has recently become the focus of several high-impact next-generation sequencing studies investigating the effect of mutations in disease and assessing the efficacy of mitochondrial replacement therapies. However, these studies have failed to take into consideration the captu...

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Dades bibliogràfiques
Publicat a:Mitochondrion
Autors principals: Santibanez-Koref, Mauro, Griffin, Helen, Turnbull, Douglass M., Chinnery, Patrick F., Herbert, Mary, Hudson, Gavin
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509278/
https://ncbi.nlm.nih.gov/pubmed/30098421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2018.08.003
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