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Mitochondrial heteroplasmy profiling in single human oocytes by next-generation sequencing
Mitochondrial DNA (mtDNA) plays a key role in the development of a competent oocyte. Mutations of the mitochondrial genome lead to an altered energetic metabolism with negative effects on oocyte developmental competence. In this study, mtDNA heteroplasmy at an intra-oocyte level and between the diff...
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| Опубликовано в: : | Mitochondrial DNA B Resour |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7800564/ https://ncbi.nlm.nih.gov/pubmed/33473893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23802359.2017.1365634 |
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