Mitochondrial heteroplasmy profiling in single human oocytes by next-generation sequencing

Mitochondrial DNA (mtDNA) plays a key role in the development of a competent oocyte. Mutations of the mitochondrial genome lead to an altered energetic metabolism with negative effects on oocyte developmental competence. In this study, mtDNA heteroplasmy at an intra-oocyte level and between the diff...

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Dades bibliogràfiques
Publicat a:Mitochondrial DNA B Resour
Autors principals: Ancora, Massimo, Orsini, Massimiliano, Colosimo, Alessia, Russo, Valentina, Marcacci, Maurilia, De Santo, Maria, D’Aurora, Marco, Stuppia, Liborio, Gatta, Valentina, Barboni, Barbara, Cammà, Cesare, Mattioli, Mauro
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Mitogenome Announcement
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7800564/
https://ncbi.nlm.nih.gov/pubmed/33473893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23802359.2017.1365634
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