Universal heteroplasmy of human mitochondrial DNA

Mammalian cells contain thousands of copies of mitochondrial DNA (mtDNA). At birth, these are thought to be identical in most humans. Here, we use long read length ultra-deep resequencing-by-synthesis to interrogate regions of the mtDNA genome from related and unrelated individuals at unprecedented...

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Hlavní autoři: Payne, Brendan A.I., Wilson, Ian J., Yu-Wai-Man, Patrick, Coxhead, Jonathan, Deehan, David, Horvath, Rita, Taylor, Robert W., Samuels, David C., Santibanez-Koref, Mauro, Chinnery, Patrick F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526165/
https://ncbi.nlm.nih.gov/pubmed/23077218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds435
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