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The Distribution of Mitochondrial DNA Heteroplasmy Due to Random Genetic Drift
Cells containing pathogenic mutations in mitochondrial DNA (mtDNA) generally also contain the wild-type mtDNA, a condition called heteroplasmy. The amount of mutant mtDNA in a cell, called the heteroplasmy level, is an important factor in determining the amount of mitochondrial dysfunction and there...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668051/ https://ncbi.nlm.nih.gov/pubmed/18976726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.10.007 |
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