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The external domains of the HIV-1 envelope are a mutational cold spot
In RNA viruses, mutations occur fast and have large fitness effects. While this affords remarkable adaptability, it can also endanger viral survival due to the accumulation of deleterious mutations. How RNA viruses reconcile these two opposed facets of mutation is still unknown. Here we show that, i...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687473/ https://ncbi.nlm.nih.gov/pubmed/26450412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9571 |
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