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Genome editing through large insertion leads to the skipping of targeted exon
BACKGROUND: Highly efficient genome editing can be achieved through targeting an endonuclease to specific locus of interest. Engineered zinc-finger nuclease (ZFN) and CRISPR-associated protein-9 nuclease (Cas9) offer such an elegant approach for genome editing in vertebrate cells. In this study, we...
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| Veröffentlicht in: | BMC Genomics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687116/ https://ncbi.nlm.nih.gov/pubmed/26691863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2284-8 |
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