The Effects of Unbound Mycophenolic Acid (MPA) on Inosine Monophosphate Dehydrogenase (IMPDH) Inhibition in Pediatric Kidney Transplant Patients

BACKGROUND: Mycophenolic acid (MPA) is a key immunosuppressive drug that acts through inhibition of inosine monophosphate dehydrogenase (IMPDH). MPA is commonly measured as part of therapeutic drug monitoring as the total concentration in plasma. However, it has been postulated that the free (unboun...

詳細記述

保存先:
書誌詳細
出版年:Ther Drug Monit
主要な著者: Smits, Thomas A., Cox, Shareen, Fukuda, Tsuyoshi, Sherbotie, Joseph, Ward, Robert, Goebel, Jens, Vinks, Alexander A.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687018/
https://ncbi.nlm.nih.gov/pubmed/24739663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000081
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