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The Effects of Unbound Mycophenolic Acid (MPA) on Inosine Monophosphate Dehydrogenase (IMPDH) Inhibition in Pediatric Kidney Transplant Patients
BACKGROUND: Mycophenolic acid (MPA) is a key immunosuppressive drug that acts through inhibition of inosine monophosphate dehydrogenase (IMPDH). MPA is commonly measured as part of therapeutic drug monitoring as the total concentration in plasma. However, it has been postulated that the free (unboun...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Ther Drug Monit |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687018/ https://ncbi.nlm.nih.gov/pubmed/24739663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000081 |
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