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The Effects of Unbound Mycophenolic Acid (MPA) on Inosine Monophosphate Dehydrogenase (IMPDH) Inhibition in Pediatric Kidney Transplant Patients

BACKGROUND: Mycophenolic acid (MPA) is a key immunosuppressive drug that acts through inhibition of inosine monophosphate dehydrogenase (IMPDH). MPA is commonly measured as part of therapeutic drug monitoring as the total concentration in plasma. However, it has been postulated that the free (unboun...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ther Drug Monit
Päätekijät: Smits, Thomas A., Cox, Shareen, Fukuda, Tsuyoshi, Sherbotie, Joseph, Ward, Robert, Goebel, Jens, Vinks, Alexander A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687018/
https://ncbi.nlm.nih.gov/pubmed/24739663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000081
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