The Effects of Unbound Mycophenolic Acid (MPA) on Inosine Monophosphate Dehydrogenase (IMPDH) Inhibition in Pediatric Kidney Transplant Patients

BACKGROUND: Mycophenolic acid (MPA) is a key immunosuppressive drug that acts through inhibition of inosine monophosphate dehydrogenase (IMPDH). MPA is commonly measured as part of therapeutic drug monitoring as the total concentration in plasma. However, it has been postulated that the free (unboun...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ther Drug Monit
Egile Nagusiak: Smits, Thomas A., Cox, Shareen, Fukuda, Tsuyoshi, Sherbotie, Joseph, Ward, Robert, Goebel, Jens, Vinks, Alexander A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687018/
https://ncbi.nlm.nih.gov/pubmed/24739663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000081
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