PHARMACOKINETIC AND PHARMACODYNAMIC ANALYSIS OF INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) ACTIVITY IN MMF-TREATED HCT RECIPIENTS

A novel approach to personalizing postgrafting immunosuppression in hematopoietic cell transplant (HCT) recipients is evaluating inosine monophosphate dehydrogenase (IMPDH) activity as a drug-specific biomarker of mycophenolic acid (MPA)-induced immunosuppression. This prospective study evaluated to...

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Autors principals: Li, Hong, Mager, Donald E., Sandmaier, Brenda M., Storer, Barry E., Boeckh, Michael J., Bemer, Meagan J., Phillips, Brian R., Risler, Linda J., McCune, Jeannine S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099316/
https://ncbi.nlm.nih.gov/pubmed/24727337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2014.03.032
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