Identification and characterization of latency-associated peptide-expressing γδ T cells

γδ T cells are a subset of lymphocytes specialized in protecting the host against pathogens and tumours. Here we describe a subset of regulatory γδ T cells that express the latency-associated peptide (LAP), a membrane-bound TGF-β1. Thymic CD27+IFN-γ+CCR9+α(4)β(7)+TCRγδ+ cells migrate to the peripher...

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Udgivet i:Nat Commun
Main Authors: Rezende, Rafael M., da Cunha, Andre P., Kuhn, Chantal, Rubino, Stephen, M'Hamdi, Hanane, Gabriely, Galina, Vandeventer, Tyler, Liu, Shirong, Cialic, Ron, Pinheiro-Rosa, Natalia, Oliveira, Rafael P., Gaublomme, Jellert T., Obholzer, Nikolaus, Kozubek, James, Pochet, Nathalie, Faria, Ana M. C., Weiner, Howard L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686827/
https://ncbi.nlm.nih.gov/pubmed/26644347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9726
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