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Rapid RNA–ligand interaction analysis through high-information content conformational and stability landscapes

The structure and biological properties of RNAs are a function of changing cellular conditions, but comprehensive, simultaneous investigation of the effect of multiple interacting environmental variables is not easily achieved. We have developed an efficient, high-throughput method to characterize R...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Baird, Nathan J., Inglese, James, Ferré-D'Amaré, Adrian R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686816/
https://ncbi.nlm.nih.gov/pubmed/26638992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9898
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