Structural studies on molecular mechanisms of Nelfinavir resistance caused by non-active site mutation V77I in HIV-1 protease

BACKGROUND: The human immunodeficiency virus (HIV-1) is a retrovirus causing acquired immunodeficiency syndrome (AIDS), which has become a serious problem across the world and has no cure reported to date. Human immunodeficiency virus (HIV-1) protease is an attractive target for antiviral treatment...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Gupta, Ankita, Jamal, Salma, Goyal, Sukriti, Jain, Ritu, Wahi, Divya, Grover, Abhinav
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686784/
https://ncbi.nlm.nih.gov/pubmed/26695135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S19-S10
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