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Structural investigations of T854A mutation in EGFR and identification of novel inhibitors using structure activity relationships
BACKGROUND: The epidermal growth factor receptor (EGFR) is a member of the ErbB family that is involved in a number of processes responsible for cancer development and progression such as angiogenesis, apoptosis, cell proliferation and metastatic spread. Malfunction in activation of protein tyrosine...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460657/ https://ncbi.nlm.nih.gov/pubmed/26041145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S5-S8 |
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