SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

Despite the recent evidence of the existence of myelodysplastic syndrome (MDS) stem cells in 5q-MDS patients, it is unclear whether haematopoietic stem cells (HSCs) could also be the initiating cells in other MDS subgroups. Here we demonstrate that SF3B1 mutation(s) in our cohort of MDS patients wit...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Mian, Syed A., Rouault-Pierre, Kevin, Smith, Alexander E., Seidl, Thomas, Pizzitola, Irene, Kizilors, Aytug, Kulasekararaj, Austin G., Bonnet, Dominique, Mufti, Ghulam J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686651/
https://ncbi.nlm.nih.gov/pubmed/26643973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10004
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