SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

Despite the recent evidence of the existence of myelodysplastic syndrome (MDS) stem cells in 5q-MDS patients, it is unclear whether haematopoietic stem cells (HSCs) could also be the initiating cells in other MDS subgroups. Here we demonstrate that SF3B1 mutation(s) in our cohort of MDS patients wit...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Mian, Syed A., Rouault-Pierre, Kevin, Smith, Alexander E., Seidl, Thomas, Pizzitola, Irene, Kizilors, Aytug, Kulasekararaj, Austin G., Bonnet, Dominique, Mufti, Ghulam J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686651/
https://ncbi.nlm.nih.gov/pubmed/26643973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10004
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares